Achalasia
From the Autoimmune Association List Only
Summary
Achalasia is a rare disorder that makes it difficult for food and liquid to pass from the swallowing tube connecting your mouth and stomach (esophagus) into your stomach.
Achalasia occurs when nerves in the esophagus become damaged. As a result, the esophagus becomes paralyzed and dilated over time and eventually loses the ability to squeeze food down into the stomach. Food then collects in the esophagus, sometimes fermenting and washing back up into the mouth, which can taste bitter. Some people mistake this for gastroesophageal reflux disease (GERD). However, in achalasia the food is coming from the esophagus, whereas in GERDthe material comes from the stomach.
There's no cure for achalasia. Once the esophagus is paralyzed, the muscle cannot work properly again. But symptoms can usually be managed with endoscopy, minimally invasive therapy or surgery.
(Autoimmune Association, 2022)
Symptoms
Achalasia symptoms generally appear gradually and worsen over time. Signs and symptoms may include:
Inability to swallow (dysphagia), which may feel like food or drink is stuck in your throat
Regurgitating food or saliva
Heartburn
Belching
Chest pain that comes and goes
Coughing at night
Pneumonia (from aspiration of food into the lungs)
Weight loss
Vomiting
(Autoimmune Association, 2022)
Diagnostic Criteria
Under Investigation
Diagnostic Tests
Under Investigation
Human Leukocyte Antigen (HLA) Associations
Under Investigation
Tissue-Type or Cell-Type Attacked
Under Investigation
Attacking Immune Cell Type or Process
Under Investigation
Treatment Modality
Under Investigation
Managing Specialist(s)
Under Investigation
Associated Infections
Under Investigation
Associated Toxins
Under Investigation
Research Authors
Under Investigation
Research Institutions
Under Investigation
Average Time from Symptom Onset to Diagnosis
Under Investigation
Last Updated
December 17, 2022
References
Achalasia. Autoimmune Association. (2022, November 09). Retrieved December 17, 2022 from https://autoimmune.org/disease-information/achalasia/