Acquired aplastic anemia

From the Global Autoimmune Institute List Only

Summary

A blood disorder that occurs when bone marrow (where red and white blood cell and platelet production occurs) is attacked by autoantibodies. This results in the body having fewer white blood cells and platelets, causing fatigue, and lowering resistance to infection. This culminates in extreme thinning of the blood leading to uncontrolled bleeding.

Severity varies from person to person, from moderately low to very low blood counts. Diagnosis is based on clinical evaluations, testing for blood cell counts, and bone marrow biopsies.

(Global Autoimmune Institute, 2022)

Symptoms

Fatigue, weakness, shortness of breath, rapid/irregular heart rate, pale skin, frequent/prolonged infections, unexplained/easy bruising, nosebleeds, bleeding gums, skin rash, dizziness, headache, and fever.

(Global Autoimmune Institute, 2022)

Diagnostic Criteria

Under Investigation

Diagnostic Tests

Under Investigation

Human Leukocyte Antigen (HLA) Associations

Under Investigation

Tissue-Type or Cell-Type Attacked

Under Investigation

Attacking Immune Cell Type or Process

Under Investigation

Treatment Modality

Under Investigation

Managing Specialist(s)

Under Investigation

Associated Infections

Under Investigation

Associated Toxins

Under Investigation

Research Authors

Under Investigation

Research Institutions

Under Investigation

Average Time from Symptom Onset to Diagnosis

Under Investigation

Last Updated

December 20, 2022

References

Acquired aplastic anemia. Global Autoimmune Institute. (2022). Retrieved December 20, 2022 from https://www.autoimmuneinstitute.org/aplastic-anemia/